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Novoline Pdf

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Novolin N has an intermediate duration of action. The effect is maximal between 4 and 12 hours. The full duration of action may last up to 24 hours after injection.

The time course of action of any insulin may vary considerably in different individuals, or at different times in the same individual.

Because of this variation, the time periods listed here should be considered as general guidance only. This human insulin recombinant DNA origin is structurally identical to the insulin produced by the human pancreas.

Do not let it freeze. Keep Novolin N PenFill cartridge in the carton so that they will stay clean and protected from light.

Unrefrigerated Novolin N PenFill cartridges must be discarded 14 days after the first use, even if they still contain Novolin N insulin.

Never use PenFill cartridges after the expiration date which is printed on the label and carton. Never use any Novolin N PenFill cartridge if the precipitate the white deposit has become lumpy or granular in appearance or has formed a deposit of solid particles on the wall of the cartridge.

This insulin should not be used if the liquid in the cartridge remains clear after it has been mixed. Failure to follow the antiseptic measures listed below may lead to infections at the injection site.

Never place a single-use disposable needle on your insulin delivery device until you are ready to give an injection, and remove it immediately after the injection.

If the needle is not removed, some liquid may be expelled from the cartridge causing a change in the insulin concentration strength. The cloudy material in an insulin suspension will settle to the bottom of the cartridge, so the contents must be mixed before injection.

These Novolin PenFill cartridges contain a glass ball to aid mixing. When using a new cartridge, turn the cartridge up and down between positions A and B - See Figure 1.

Do this at least 10 times until the liquid appears uniformly white and cloudy. For subsequent injections when a cartridge is already in the device, turn the device up and down between positions A and B - See Figure 2.

Follow the directions in your insulin delivery device instruction manual. Note: Never initiate a new injection unless there is sufficient insulin in the cartridge to ensure proper mixing the glass ball needs adequate room for movement to mix the suspension.

PenFill cartridges may contain a small amount of air bubbles. To prevent an injection of air and to make certain a full dose of insulin is injected, an air shot must be done before each injection.

Directions for performing an air shot are provided in your delivery device instruction manual. The following areas are suitable for subcutaneous insulin injection: thighs, upper arms, buttocks, abdomen.

Do not change areas without consulting your physician. The actual point of injection should be changed each time; injection sites should be about an inch apart.

The injection site should be clean and dry. Pinch up skin area to be injected and hold it firmly. Hold the device like a pencil and push the needle quickly and firmly into the pinched-up area.

Release the skin and push the push button all the way in to inject insulin beneath the skin. After the injection, the needle should remain under the skin for at least 6 seconds.

Keep the push button fully depressed until the needle is withdrawn from the skin. This will ensure that the full dose has been injected.

Do not inject into a muscle unless your physician has advised it. You should never inject insulin into a vein. Follow the directions for use of your insulin delivery device.

Remove the needle. If slight bleeding occurs, press lightly with a dry cotton swab for a few seconds - do not rub. It is particularly important to maintain good control of your diabetes during pregnancy and special attention must be paid to your diet, exercise and insulin regimens.

If you are pregnant or nursing a baby, consult your physician or nurse educator. Insulin reaction hypoglycemia occurs when the blood glucose falls very low.

This can happen if you take too much insulin, miss or delay a meal, exercise more than usual, or work too hard without eating, or become ill especially with vomiting or fever.

Hypoglycemia can also happen if you combine insulin therapy and other medications that lower blood glucose, such as oral antidiabetic agents or other prescription and over-the-counter drugs.

The first symptoms of an insulin reaction usually come on suddenly. They may include a cold sweat, fatigue, nervousness or shakiness, rapid heartbeat, or nausea.

Personality change or confusion may also occur. If you drink or eat something right away a glass of milk or orange juice, or several sugar candies , you can often stop the progression of symptoms.

If symptoms persist, call your physician - an insulin reaction can lead to unconsciousness. If a reaction results in loss of consciousness, emergency medical care should be obtained immediately.

If you have had repeated reactions or if an insulin reaction has led to a loss of consciousness, contact your physician. Severe hypoglycemia can result in temporary or permanent impairment of brain function and death.

In certain cases, the nature and intensity of the warning symptoms of hypoglycemia may change. A few patients have reported that after being transferred to human insulin, the early warning symptoms of hypoglycemia were less pronounced than they had been with animal-source insulin.

Diabetic ketoacidosis may develop if your body has too little insulin. The most common causes are acute illness or infection or failure to take enough insulin by injection.

If you are ill, you should check your urine for ketones. The symptoms of diabetic ketoacidosis usually come on gradually, over a period of hours or days, and include a drowsy feeling, flushed face, thirst and loss of appetite.

Notify your physician right away if the urine test is positive for ketones acetone or if you have any of these symptoms.

Fast, heavy breathing and rapid pulse are more severe symptoms and you should have medical attention right away. Severe, sustained hyperglycemia may result in diabetic coma and death.

A few people with diabetes develop red, swollen and itchy skin where the insulin has been injected. Generalized insulin allergy occurs rarely, but when it does it may cause a serious reaction, including skin rash over the body, shortness of breath, fast pulse, sweating, and a drop in blood pressure.

If any of these symptoms develop, you should seek emergency medical care. If severe allergic reactions to insulin have occurred i.

A change in the type, strength, species or purity of insulin could require a dosage adjustment. Any change in insulin should be made under medical supervision.

Before use, check that the PenFill cartridge is intact e. Do not use if any damage is visible, or if the part of the rubber piston that you see is wider than the white bar code band.

You may have learned how to test your urine or your blood for glucose. It is important to do these tests regularly and to record the results for review with your physician or nurse educator.

If you have an acute illness, especially with vomiting or fever, continue taking your insulin. If possible, stay on your regular diet.

If you have trouble eating, drink fruit juices, regular soft drinks, or clear soups; if you can, eat small amounts of bland foods.

Test your urine for glucose and ketones and, if possible, test your blood glucose. Note the results and contact your physician for possible insulin dose adjustment.

If you have severe and prolonged vomiting, seek emergency medical care. Always consult your physician if you have any questions about your condition or the use of insulin.

Protected by U. Patent No. Do this at least 10 times, until the liquid appears uniformly white and cloudy. To ensure even mixing of the remaining insulin there must be at least 12 units of insulin left in the reservoir.

Remove the needle immediately after use. Small amounts of air may collect in the needle and insulin reservoir during normal use.

To avoid the injection of air and ensure proper dosing, dial 2 units by turning the dose selector clockwise. Remove both the plastic outer and inner needle caps.

With the needle pointing up, press the push button as far as it will go and the dose selector returns to zero. See if a drop of insulin appears at the needle tip see fig.

If not, repeat the procedure until insulin appears. If you need to make more than 6 air shots, do not use, and return the product to Novo Nordisk.

A small air bubble may remain but it will not be injected because the operating mechanism prevents the reservoir from being completely emptied.

Always check that the push button is fully depressed and the dose selector is set to zero. Do not put your hand over the push button when dialing the dose.

If the button is not allowed to rise freely, insulin will be pushed out of the needle. When setting your dose, you will hear a click for every single unit dialed.

Do not rely on this clicking sound as a means of determining your dose. You should not use insulin if you are having an episode of hypoglycemia low blood sugar.

You should not use Novolin R if you are allergic to insulin, or if you are having an episode of hypoglycemia low blood sugar. Regular insulin is not approved for use by anyone younger than 2 years old.

Regular insulin should not be used to treat type 2 diabetes in a child of any age. Taking certain oral diabetes medicines while using insulin may increase your risk of serious heart problems.

Tell your doctor if you also take medicine that contains pioglitazone or rosiglitazone. Follow your doctor's instructions about using insulin if you are pregnant or you become pregnant.

Controlling diabetes is very important during pregnancy, and having high blood sugar may cause complications in both the mother and the baby.

Follow all directions on your prescription label and read all medication guides or instruction sheets.

Use the medicine exactly as directed. Regular insulin is injected under the skin. A healthcare provider can teach you how to properly use the medication by yourself.

Regular insulin must not be given with an insulin pump. Do not inject regular insulin into a vein or a muscle. Read and carefully follow any Instructions for Use provided with your medicine.

Ask your doctor or pharmacist if you don't understand all instructions. Prepare an injection only when you are ready to give it.

Do not use if the medicine looks cloudy, has changed colors, or has particles in it. Call your pharmacist for new medicine.

Prepare your injection only when you are ready to give it. Your care provider will show you where on your body to inject insulin. Use a different place each time you give an injection.

Do not inject into the same place two times in a row. Do not inject this medicine into skin that is damaged, tender, bruised, pitted, thickened, scaly, or has a scar or hard lump.

Never share a syringe with another person, even if the needle has been changed. Sharing syringes can allow infections or disease to pass from one person to another.

You may have low blood sugar hypoglycemia and feel very hungry, dizzy, irritable, confused, anxious, or shaky. To quickly treat hypoglycemia, eat or drink a fast-acting source of sugar fruit juice, hard candy, crackers, raisins, or non-diet soda.

Your doctor may prescribe a glucagon injection kit in case you have severe hypoglycemia. Be sure your family or close friends know how to give you this injection in an emergency.

Blood sugar levels can be affected by stress , illness, surgery, exercise, alcohol use, or skipping meals. Ask your doctor before changing your dose or medication schedule.

Insulin is only part of a complete treatment program that may also include diet, exercise, weight control, blood sugar testing, and special medical care.

Follow your doctor's instructions very closely. Keep this medicine in its original container protected from heat and light.

Do not freeze insulin or store it near the cooling element in a refrigerator. Throw away any insulin that has been frozen. Refrigerate and use until expiration date ; or.

Use a needle and syringe only once and then place them in a puncture-proof "sharps" container. Follow state or local laws about how to dispose of this container.

Keep it out of the reach of children and pets. Use the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose.

Do not use two doses at one time. Keep insulin on hand at all times.

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The cloudy material in an insulin suspension will settle to the bottom of the cartridge, so the contents must be mixed before injection.

These Novolin PenFill cartridges contain a glass ball to aid mixing. When using a new cartridge, turn the cartridge up and down between positions A and B - See Figure 1.

Do this at least 10 times until the liquid appears uniformly white and cloudy. For subsequent injections when a cartridge is already in the device, turn the device up and down between positions A and B - See Figure 2.

Follow the directions in your insulin delivery device instruction manual. Note: Never initiate a new injection unless there is sufficient insulin in the cartridge to ensure proper mixing the glass ball needs adequate room for movement to mix the suspension.

PenFill cartridges may contain a small amount of air bubbles. To prevent an injection of air and to make certain a full dose of insulin is injected, an air shot must be done before each injection.

Directions for performing an air shot are provided in your delivery device instruction manual. The following areas are suitable for subcutaneous insulin injection: thighs, upper arms, buttocks, abdomen.

Do not change areas without consulting your physician. The actual point of injection should be changed each time; injection sites should be about an inch apart.

The injection site should be clean and dry. Pinch up skin area to be injected and hold it firmly.

Hold the device like a pencil and push the needle quickly and firmly into the pinched-up area. Release the skin and push the push button all the way in to inject insulin beneath the skin.

After the injection, the needle should remain under the skin for at least 6 seconds. Keep the push button fully depressed until the needle is withdrawn from the skin.

This will ensure that the full dose has been injected. Do not inject into a muscle unless your physician has advised it. You should never inject insulin into a vein.

Follow the directions for use of your insulin delivery device. Remove the needle. If slight bleeding occurs, press lightly with a dry cotton swab for a few seconds - do not rub.

It is particularly important to maintain good control of your diabetes during pregnancy and special attention must be paid to your diet, exercise and insulin regimens.

If you are pregnant or nursing a baby, consult your physician or nurse educator. Insulin reaction hypoglycemia occurs when the blood glucose falls very low.

This can happen if you take too much insulin, miss or delay a meal, exercise more than usual, or work too hard without eating, or become ill especially with vomiting or fever.

Hypoglycemia can also happen if you combine insulin therapy and other medications that lower blood glucose, such as oral antidiabetic agents or other prescription and over-the-counter drugs.

The first symptoms of an insulin reaction usually come on suddenly. They may include a cold sweat, fatigue, nervousness or shakiness, rapid heartbeat, or nausea.

Personality change or confusion may also occur. If you drink or eat something right away a glass of milk or orange juice, or several sugar candies , you can often stop the progression of symptoms.

If symptoms persist, call your physician - an insulin reaction can lead to unconsciousness. If a reaction results in loss of consciousness, emergency medical care should be obtained immediately.

If you have had repeated reactions or if an insulin reaction has led to a loss of consciousness, contact your physician.

Severe hypoglycemia can result in temporary or permanent impairment of brain function and death. In certain cases, the nature and intensity of the warning symptoms of hypoglycemia may change.

A few patients have reported that after being transferred to human insulin, the early warning symptoms of hypoglycemia were less pronounced than they had been with animal-source insulin.

Diabetic ketoacidosis may develop if your body has too little insulin. The most common causes are acute illness or infection or failure to take enough insulin by injection.

If you are ill, you should check your urine for ketones. The symptoms of diabetic ketoacidosis usually come on gradually, over a period of hours or days, and include a drowsy feeling, flushed face, thirst and loss of appetite.

Notify your physician right away if the urine test is positive for ketones acetone or if you have any of these symptoms. Fast, heavy breathing and rapid pulse are more severe symptoms and you should have medical attention right away.

Severe, sustained hyperglycemia may result in diabetic coma and death. A few people with diabetes develop red, swollen and itchy skin where the insulin has been injected.

Generalized insulin allergy occurs rarely, but when it does it may cause a serious reaction, including skin rash over the body, shortness of breath, fast pulse, sweating, and a drop in blood pressure.

If any of these symptoms develop, you should seek emergency medical care. If severe allergic reactions to insulin have occurred i.

A change in the type, strength, species or purity of insulin could require a dosage adjustment. Any change in insulin should be made under medical supervision.

Before use, check that the PenFill cartridge is intact e. Do not use if any damage is visible, or if the part of the rubber piston that you see is wider than the white bar code band.

You may have learned how to test your urine or your blood for glucose. It is important to do these tests regularly and to record the results for review with your physician or nurse educator.

If you have an acute illness, especially with vomiting or fever, continue taking your insulin. If possible, stay on your regular diet. If you have trouble eating, drink fruit juices, regular soft drinks, or clear soups; if you can, eat small amounts of bland foods.

Test your urine for glucose and ketones and, if possible, test your blood glucose. Note the results and contact your physician for possible insulin dose adjustment.

If you have severe and prolonged vomiting, seek emergency medical care. Always consult your physician if you have any questions about your condition or the use of insulin.

Protected by U. Patent No. Do this at least 10 times, until the liquid appears uniformly white and cloudy. To ensure even mixing of the remaining insulin there must be at least 12 units of insulin left in the reservoir.

Remove the needle immediately after use. Small amounts of air may collect in the needle and insulin reservoir during normal use.

To avoid the injection of air and ensure proper dosing, dial 2 units by turning the dose selector clockwise. Remove both the plastic outer and inner needle caps.

With the needle pointing up, press the push button as far as it will go and the dose selector returns to zero.

See if a drop of insulin appears at the needle tip see fig. If not, repeat the procedure until insulin appears. If you need to make more than 6 air shots, do not use, and return the product to Novo Nordisk.

A small air bubble may remain but it will not be injected because the operating mechanism prevents the reservoir from being completely emptied. Always check that the push button is fully depressed and the dose selector is set to zero.

Do not put your hand over the push button when dialing the dose. If the button is not allowed to rise freely, insulin will be pushed out of the needle.

When setting your dose, you will hear a click for every single unit dialed. Do not rely on this clicking sound as a means of determining your dose. If you have set a wrong dose, simply dial the dose selector forward or backwards until the right number of units has been set.

Use the injection technique recommended by your doctor. Check that you have set the proper dose and depress the push button as far as it will go.

Make sure not to block the dose selector while injecting as the dose selector must be allowed to return to zero when you press the push button.

When depressing the push button you may hear a clicking sound. Do not rely on this clicking sound as a means of confirming delivery of your dose.

After making the injection, unscrew the needle and discard appropriately. Replace the device cap. Health care professionals, relatives, and other care-givers should follow general precautionary measures for removal and disposal of needles to eliminate the risk of unintended needle penetration.

For additional information see Giving the injection on the reverse side of this insert. If not, turn the dose selector until the push button is completely down.

Then proceed as stated under steps These numbers are not used for measuring the insulin dose. Novo Nordisk cannot be held responsible for adverse reactions occurring as a consequence of using the insulin delivery system with products that are not recommended by Novo Nordisk.

Patents Nos. Controlling diabetes is very important during pregnancy, and having high blood sugar may cause complications in both the mother and the baby.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Regular insulin is injected under the skin. A healthcare provider can teach you how to properly use the medication by yourself.

Regular insulin must not be given with an insulin pump. Do not inject regular insulin into a vein or a muscle. Read and carefully follow any Instructions for Use provided with your medicine.

Ask your doctor or pharmacist if you don't understand all instructions. Prepare an injection only when you are ready to give it. Do not use if the medicine looks cloudy, has changed colors, or has particles in it.

Call your pharmacist for new medicine. Prepare your injection only when you are ready to give it. Your care provider will show you where on your body to inject insulin.

Use a different place each time you give an injection. Do not inject into the same place two times in a row. Do not inject this medicine into skin that is damaged, tender, bruised, pitted, thickened, scaly, or has a scar or hard lump.

Never share a syringe with another person, even if the needle has been changed. Sharing syringes can allow infections or disease to pass from one person to another.

You may have low blood sugar hypoglycemia and feel very hungry, dizzy, irritable, confused, anxious, or shaky.

To quickly treat hypoglycemia, eat or drink a fast-acting source of sugar fruit juice, hard candy, crackers, raisins, or non-diet soda. Your doctor may prescribe a glucagon injection kit in case you have severe hypoglycemia.

Be sure your family or close friends know how to give you this injection in an emergency. Blood sugar levels can be affected by stress , illness, surgery, exercise, alcohol use, or skipping meals.

Ask your doctor before changing your dose or medication schedule. Insulin is only part of a complete treatment program that may also include diet, exercise, weight control, blood sugar testing, and special medical care.

Follow your doctor's instructions very closely. Keep this medicine in its original container protected from heat and light. Do not freeze insulin or store it near the cooling element in a refrigerator.

Throw away any insulin that has been frozen. Refrigerate and use until expiration date ; or. Use a needle and syringe only once and then place them in a puncture-proof "sharps" container.

Follow state or local laws about how to dispose of this container. Keep it out of the reach of children and pets. Use the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose.

Do not use two doses at one time. Keep insulin on hand at all times. Get your prescription refilled before you run out of medicine completely.

Seek emergency medical attention or call the Poison Help line at Insulin overdose can cause life-threatening hypoglycemia.

Symptoms include drowsiness, confusion, blurred vision, numbness or tingling in your mouth, trouble speaking, muscle weakness, clumsy or jerky movements, seizure convulsions , or loss of consciousness.

Do not change the brand of insulin or syringe you are using without first talking to your doctor or pharmacist. Some brands of insulin and syringes are interchangeable, while others are not.

Insulin can cause low blood sugar.

It is particularly important to maintain Novoline Pdf control of your diabetes during pregnancy and special attention must be paid to your diet, exercise and Spiele Mein Tom regimens. Follow state or local laws about how to dispose of this container. This is not a complete list of side effects and others may occur. Do not rely on this Clixsense Erfahrung sound as a means of English Championship delivery of your dose. You may have learned how to test your urine or your blood for glucose. Use Pool 8 Play Online injection technique recommended by your doctor. Do not use if any damage is visible, or if the part of the rubber piston that you see is wider than the white bar code band. Novoline Pdf

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